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Subtype-specific neutralizing antibodies promote antigenic shift during influenza virus co-infection

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LIU Meng-nan

8.0 MB

The conundrum of how pre-existing humoral immunity orchestrates the emergence of novel viral strains via reassortment remains a enigma. Our study elucidated the intricate dynamics by which strain-specific and broadly reactive antibodies interact to modulate the genetic diversity and evolutionary paradigm of influenza viruses.

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