Abstract This open-access release provides an emic grammar note on selected morphosyntactic and pragmatic constructions in Jiepai speech, a local Sinitic speech variety from the Wu-Jianghuai contact zone in Jiepai, Danyang, Jiangsu, China. The file is prepared as a grammar appendix to the Jiepai Jianghu section of the Chuanyue archive, an emic vernacular multimodal archive created by a native insider. The note documents selected structures in grammar, syntax, aspect, disposal, passive-related expression, locative marking, shared-use constructions, degree expression, and pragmatic usage. It includes notes on ge marking; completion-question and negative-completion forms such as geng and beng; aspectual distinctions related to Mandarin le and zhe; na disposal constructions; ha / bo constructions across passive, giving, and marriage-related contexts; locative suffixes; go shared-use constructions; yanlian parallel-action structures; degree adverbs and ironic intensification; and locative lai2 / A patterns. The document is based on the Archive Author's native-speaker knowledge and ongoing documentation of Jiepai speech. It does not present a complete grammar, final character standardization, final IPA transcription, phonetic analysis, or ELAN alignment. Phonetic, tonal, and character-form notes marked as provisional or pending verification are retained as research openings rather than resolved conclusions. Authorship and deposit roles are separate. The Archive Author, The Jiepai Archivist, is the creator, archive owner, rights holder, and public contact person. The uploader provides curatorial and deposit assistance only and is not the author, creator, archive owner, rights holder, or public contact for this archive.
These datasets were collected using a total of 585 Armadillidium vulgare females. The objective of this study was to measure survival after immune priming with Salmonella enterica , using different doses and inactivation methods, and to characterise the underlying cellular mechanisms using flow cytometry. Survival analysis according to S. enterica method of inactivation and dosage Survival after injection of a lethal dose of live S. enterica was measured after immune priming using bacteria inactivated by heat (HK) or paraformaldehyde (PFA) and two different doses (10^3 and 10^6). This allowed to collect the Dataset_survival.csv, analysed using the Script_survival_analysis.R. Dataset_survival.csv: Ind: individual identification Treatment: priming treatment that females received. C : control females, no priming injection. PBS : females primed with sterile PBS. PFA3 / PFA6 : females primed with 10^3 or 10^6 PFA-inactivated S. enterica . HK3 / HK6 : females primed with 10^3 or 10^6 heat-inactivated S. enterica . Repl: experimental replicate Status: 1 = dead, 0 = live Survival : Time at death. 168 indicates living females at the end of the experiment Time: Time elapsed between the two injections. T24 : 24hours. T7 : 7 days Haemocyte sub-populations analysis according to priming treatment Following the survival experiment, and because the A. vulgare primed with PFA6 inactivated S. enterica exhibited the highest survival rates against LD50 infection, this inactivated method and dosage were used to examine the haemocyte sub-populations of A. vulgare mounting immune priming. Haemolymph was sampled from all females (C, PBS, PFA6) either 2 days (2D-PP) or 6 days (6D-PP) after the initial priming injection, or 2 days after the LD50 injection (2D-LD50). Distinct sets of females were used for each time point. This allowed to generate the Dataset_cytometry.csv, analysed using the Script_cytometry_pca_analysis.R. Principal Component Analysis (PCA) for each observation time allowed to extract projection values of the four PCs for each individual (Dataset_pca_ind_coord.csv). Dataset_cytometry.csv: Ind: individual identification Treatment: priming treatment that females received. C: control females, no priming injection. PBS: females primed with sterile PBS. PFA6: 10^6 PFA-inactivated S. enterica . Repl: experimental replicate Box: experimental box Exp: experimental day Time: Sampling time. 2D-PP: 2-days after priming. 6D-PP: 6-days after the priming injection. 2D-LD50: 2 days after the LD50 infection. P1_percent: Percentage of the first population. P1_FSCA: Cell diameter (size) of the first population. P1_SSCA: Internal complexity (internal granularity) of the first population. Viab_P1: Viability of the first population. P2_percent: Percentage of the second population. P2_FSCA: Cell diameter (size) of the second population. P2_SSCA: Internal complexity (internal granularity) of the second population. Viab_P2: Viability of the second population. Dataset_pca_ind_coord .csv: Ind: individual identification Treatment: priming treatment that females received. C: control females, no priming injection. PBS: females primed with sterile PBS. PFA6: 10^6 PFA-inactivated S. enterica . Repl: experimental replicate Box: experimental box Exp: experimental day Time: Sampling time. 2D-PP: 2-days after priming. 6D-PP: 6-days after the priming injection. 2D-LD50: 2 days after the lethal dose infection. Dim.1: projection values on the first principal component (PC1) for each individual. Dim.2: projection values on the second principal component (PC2) for each individual. Dim.3: projection values on the third principal component (PC3) for each individual. Dim.4: projection values on the fourth principal component (PC4) for each individual.
Poonia, NIkita · Saraswat, Dr. Niraja · Poonia, Dr. Arun Kumar
7 files · 107 KB · pdf
This repository contains the dataset associated with the study " Structured to Fail: Gender Bias in Large Language Models Across Text and Visual Modalities Through Data Feminism and Intersectionality in the Indian Context". The deposit includes a representative subset of the full study data, comprising the following components: Sample Design: Documentation of the sampling framework and run structure across the three LLM platforms examined Prompt Battery: The complete set of prompts administered across text and image generation tasks Model-Generated Text Outputs: Textual responses generated (1,020) by the models under the study Model-Generated Image Outputs: Visual outputs generated (480) in response through image-generation prompts Codebook: Provides complete instructions for all independent coders participating in the inter-rater reliability (IRR) study Inter-rater Reliability Dataset: The double-coded subset used to establish coding agreement Reported Reliability Scores: Cohen's Kappa values and percentage agreement statistics as reported in the manuscript
Dataset containing the systematic review matrix and extracted variables supporting the article "Bridging ecological restoration and social legitimacy: a systematic review of Cultural Ecosystem Services in inland aquatic ecosystems", accepted for publication in People and Nature.
Der Datensatz "Intensivkapazitäten und COVID-19-Intensivbettenbelegung in Deutschland" des Robert Koch-Instituts dokumentiert die tägliche intensivmedizinische Versorgungslage seit der COVID-19-Pandemie. Basierend auf Meldungen aller intensivbettenführenden Krankenhäuser in Deutschland erfasst das DIVI-Intensivregister Echtzeitdaten zu belegten und freien Intensivbetten. Die Erhebung differenziert nach Altersgruppen, Regionen und Versorgungsstufen. COVID-19-Fälle auf Intensivstationen werden gesondert ausgewiesen. Die Daten stehen aggregiert auf Bundes-, Landes- und Kreisebene zur Verfügung. Damit bildet der Datensatz eine Grundlage für die Überwachung von Kapazitäten, die Koordination von Behandlungskapazitäten und politische Entscheidungsprozesse während der Pandemie und darüber hinaus.
Al-awar, Rima · Aman, Ahmed · Briggs, Mike · et al.
999 rows × 26 cols · 8.8 MB · pdf, xlsx
26 categorical
Diffuse Intrinsic Pontine Glioma (DIPG) is a rare and aggressive pediatric cancer located in the pons region of the brainstem, classified as a broader class of H3 K27M mutant Diffuse Midline Gliomas (DMG). Traditional drug development models struggle to address rare diseases like DIPG due to small patient populations and high risks. M4K Pharma focuses on developing an ALK2 enzyme inhibitor, the first therapeutic designed specifically for DIPG. We are leveraging highly potent, selective, and drug-like molecules targeting this protein to create a promising therapeutic option for children affected by this devastating disease. The following entries include the PK and DMPK evaluation of ALK2 inhibitor compounds, including M4K2009, M4K2281, and M4K2308, across a series of in vivo mouse studies. The datasets include oral (PO) and intraperitoneal (IP) exposure analyses, dose-escalation studies, formulation comparisons, BBB penetration assessments, tissue distribution measurements, and study protocols outlining dosing regimens, sample collection procedures, and bioanalytical methodologies. In addition, the studies characterize the metabolic conversion of M4K2281 to M4K2308 through N-demethylation and compare the brain exposure profiles of multiple ALK2 inhibitor candidates. Together, this data provides an integrated assessment of systemic exposure, tissue distribution, metabolic stability, and central nervous system penetration to support the selection and optimization of brain-penetrant ALK2 inhibitors for DIPG. The accompanying files also include key pharmacokinetic parameters, including Cmax, area under the curve (AUC), half-life (T½), mean residence time (MRT), dose proportionality analyses, and brain-to-plasma ratio measurements that inform compound progression into IND-enabling development. Table of key terms and definitions of the project. Key Term Definition Pharmacokinetics (PK) The study of how a drug is absorbed, distributed, metabolized, and eliminated over time within the body. Drug Metabolism and Pharmacokinetics (DMPK) The evaluation of a compound's absorption, distribution, metabolism, excretion, and overall exposure to support drug development. Blood-Brain Barrier (BBB) A highly selective barrier that regulates the movement of substances from the bloodstream into the brain and limits drug delivery to CNS tumors. Oral (PO) Administration Delivery of a drug by mouth to achieve systemic absorption and exposure. Intraperitoneal (IP) Administration Administration of a drug into the peritoneal cavity to achieve systemic exposure in animal studies. M4K2009 Lead orally bioavailable ALK2 inhibitor selected for development due to its favourable exposure and brain penetration properties. M4K2281 ALK2 inhibitor precursor compound that undergoes metabolic N-demethylation to form M4K2308. M4K2308 Brain-penetrant ALK2 inhibitor metabolite that demonstrates improved CNS exposure and favourable brain-to-plasma ratios. N-demethylation A metabolic process that removes a methyl group from a molecule, converting M4K2281 into M4K2308. Brain-to-Plasma Ratio A metric used to quantify CNS penetration by comparing drug concentrations in brain tissue relative to plasma concentrations. Dose Proportionality The relationship between dose and systemic exposure, where exposure increases proportionally as dose increases. Tissue Distribution The extent to which a compound is distributed into specific tissues, including brain and skeletal muscle. LC-MS/MS Liquid chromatography-tandem mass spectrometry; an analytical technique used to quantify drug concentrations in biological samples.
Burgardt, Sabrina · Feß, Julian · Guthmann, Alexander · et al.
1 files · 43 MB · zip
Data sets as plotted in the preprint "Quantum-enabled active matter at the atomic scale" are uploaded. The zip file "data" contains a folder for each figure in the preprint (named after the figure). Each folder contains the data for all graphs in the respective figure.
Cell characterisation and aging data for a 280 Ah prismatic LFP cell. This data is for the 'LIC' cell from EU Horizon Project: TEMPEST. The following data is included: (1) Capacity tests and HPPC tests at 15, 20, 25, 30, and 35 °C (capacity_hppc_entropy.zip). (2) Entropy coefficient measurements at 0.1, 0.3, 0.5, 0.7, and 0.9 SoC (capacity_hppc_entropy.zip). (3) Aging data for 700 cycles including the raw cycling data and reference performance tests (aging.zip).
Mycotheca ( MYCL ) is an independent fungarium created to provide fungal specimens and open data to the scientific community. It emerged from the need to document and preserve Chilean funga but also to guarantee access to the information generated in the process. Each record in the database follows the guidelines of the Darwin Core standard in line with the FAIR principles . This project is not affiliated with any government or academic institution and is funded entirely by voluntary contributions from Patreon members.
Estimates and R codes of immigration flow proportions by age, sex and education of 199 countries between 1990-1995 to 2015-2020 based on methods presented in Yildiz and Abel (2026). Version v2: Updated R scripts to extend the range of Random Forest models considered in the main SL algorithm and to include a more diverse SL algorithm, and revised output table. Immigration composition by SL provides the results by the Super Learner model with six columns for each of the data dimensions: iso3c: Destination ISO three letter country code period: Five-year periods age: Five-year ge groups sex education: Educational attainment prop: Proportion of immigration flow.
Recombinant human diamine oxidase prevents hemodynamic effects of continuous histamine infusion in guinea pigs Author: Weiss-Tessbach, Matthias (Contact person) Department of Clinical Pharmacology, Medical University of Vienna, Austria Description Data from : Recombinant human diamine oxidase prevents hemodynamic effects of continuous histamine infusion in guinea pigs Related publication: Inflammation Research (2023), DOI: 10.1007/s00011-023-01783-3 Description of the data and file structure Experimental data from 38 female Dunkin-Hartley guinea pigs studied in an anaesthetised, continuous intravenous histamine-infusion model of histamine-induced shock, testing whether recombinant human diamine oxidase with a mutated heparin-binding motif (rhDAO_mHBM) prevents histamine-induced haemodynamic effects. The study comprised rhDAO pharmacokinetics (2 mg/kg), endogenous diamine oxidase release after heparin, histamine dose-finding, a main experiment at 8 µg/kg/min histamine with buffer / rhDAO 2 mg/kg / rhDAO 4 mg/kg, and urinary metabolite measurements. Data are in tidy (long) format: one measurement per row. time_min is minutes from the start of the histamine infusion (0 = start); in the main experiment histamine was infused from 10 to 40 min. An empty cell means not measured. Units are given in each column header. Files and variables File : GP_rhDAO_histamine_dataset_FWF_P36105.xlsx Description : A single Excel workbook containing a README sheet, an Animals metadata sheet, six measurement sheets, and a Figure_map sheet linking each sheet to the corresponding published figure. Variables Sheet: Animals - GP_ID - animal identifier (GP1-GP42) - sex - female - strain - Dunkin-Hartley - body_weight_g - body weight in g - experiment_role - role in the study (heparin, method/urine, dose-finding, PK/pilot, pilot, main, cohort) - treatment_group - treatment received (buffer, rhDAO 2 mg/kg, rhDAO 4 mg/kg, NaCl, histamine only, etc.) - histamine_dose_ug_kg_min - histamine infusion rate in µg/kg/min (a range for dose-finding animals) - rhDAO_dose_mg_kg - rhDAO dose in mg/kg, if given - in_publication - whether the animal contributes to a published figure (Yes/No) - figures - figures in which the animal appears - notes - fate / experimental notes Sheet: Hemodynamics - GP_ID - animal identifier - treatment_group - treatment received - phase - experiment phase (main, dose-finding, pilot, rhDAO PK) - time_min - minutes from start of histamine infusion (0 = start) - HR_bpm - heart rate in beats/min - MAP_mmHg - mean arterial pressure in mmHg - body_temp_C - core body temperature in °C Sheet: Plasma_histamine - GP_ID - animal identifier - treatment_group - treatment received - time_min - minutes from infusion start - histamine_ng_mL - plasma histamine in ng/mL - assay - assay method (Immunotech immunoassay; main experiment) Sheet: Plasma_rhDAO - GP_ID - animal identifier - treatment_group - treatment received - phase - Fig 1a PK or Fig 3c main experiment - time_min - minutes from infusion start - rhDAO_ug_mL - plasma recombinant human diamine oxidase in µg/mL - assay - DAO antigen ELISA Sheet: Endogenous_DAO_heparin - GP_ID - animal identifier (GP1-GP4) - time_min - 0 = baseline; 5 = 5 min after 500 IU/kg heparin i.v. - DAO_activity_ng_mL - endogenous diamine oxidase in ng/mL - note - sampling context Sheet: Blood_gas - GP_ID - animal identifier - treatment_group - treatment received - time_min - 0 or 60 min - lactate_mmol_L - arterial lactate in mmol/L - pO2_mmHg - arterial oxygen partial pressure in mmHg - pCO2_mmHg - arterial carbon dioxide partial pressure in mmHg Sheet: Urine - GP_ID - animal identifier - group - group annotation from the source records - time_min - collection time in min - creatinine_mg_dL - urinary creatinine in mg/dL - histamine_ng_mL - urinary histamine in ng/mL - methylhistamine_ng_mL - urinary 1-methylhistamine in ng/mL - His_per_Krea - histamine / creatinine ratio - MHis_per_Krea - 1-methylhistamine / creatinine ratio Sheet: Figure_map - figure - published figure - description - what the figure shows - animals - animals included - sheet - sheet (and filter) that reproduces the figure Abbreviations: rhDAO = recombinant human diamine oxidase; DAO = diamine oxidase; MAP = mean arterial pressure; HR = heart rate; His = histamine; 1-MH/MHis = 1-methylhistamine; Krea = creatinine; EIA/ELISA = enzyme immunoassay; HTRF = homogeneous time-resolved fluorescence; i.v./i.a. = intravenous/intra-arterial. Note on assays: main-experiment plasma histamine (GP21-32) was measured by the Immunotech immunoassay; dose-finding/pilot plasma histamine was measured by Cisbio HTRF, so absolute values between methods are not directly comparable. Urinary metabolites were measured using LC-MS/MS. Code/software Data can be opened in Microsoft Excel or LibreOffice Calc, or imported into R or Python (e.g., readxl, pandas/openpyxl). Animal welfare and ethics All animal procedures were approved by the Austrian Federal Ministry of Education, Science and Research (BMBWF) and performed at the Division of Biomedical Research, Medical University of Vienna, under animal protocol GZ 2021-0.209.778. The study used 38 female Dunkin-Hartley guinea pigs. Funding: Austrian Science Fund (FWF), award P36105 (Hertha-Firnberg programme T1135).
Kárpi, Marcell · Szalai, Sándor · Baracza, Mátyás Krisztián
1 files · 1.1 MB · zip
Geoelectric raw data, measured with an Iris Syscal Pro Switch 72, in the park of the University of Miskolc. The data are in .bin format, which can be opened and managed by the free software Prosys II: (Dowload link: https://www.iris-instruments.com/download.html). The used geoelectric arrays are the Wenner-alpha, dipole-dipole, and a quasi-null array G112. In the years we did measurement, precipitation data is also attached. Lithology is given in a table.
This dataset contains the results of information exposure identification conducted on public SMA, SMK, and MA school websites in Malang City, Indonesia. The data were collected using Google Dorking techniques as part of an Open Source Intelligence (OSINT) approach. The dataset includes information about website samples, detected information exposure categories, and risk classifications. Sensitive information has been anonymized to ensure privacy and ethical compliance.
40 RGB PNG frames of ERA5 vertically integrated water-vapour transport (IVT) magnitude over the North Pacific, 6-hourly from 2 to 11 February 2017, derived from the public ARCO-ERA5 archive (IVT = sqrt(u^2 + v^2)). Each frame renders an atmospheric river as a bright filament on a dark background and is named NPacific_IVT_0000.png ... NPacific_IVT_0039.png. This is the Earth-observation dataset for the Galaxy Training Network tutorial 'Object tracking using CellProfiler' (https://gxy.io/GTN:T00516), used to demonstrate that a CellProfiler nucleus-tracking pipeline can be reused to detect and track atmospheric rivers. Preprocessing notebooks, full Galaxy run provenance, and the software archive: https://github.com/annefou/fiesta-galaxy-cellprofiler-eo (DOI 10.5281/zenodo.20811614). Part of the OSCARS-FIESTA project.
This dataset was collected to investigate the multi-omic mechanisms underlying photosynthesis-driven interactions within the phycosphere, specifically focusing on how these interactions regulate and enhance bacterial extracellular superoxide production under carbon-starvation conditions. Experimental efforts involved co-culturing the cyanobacterium Microcystis aeruginosa and the heterotrophic bacterium Pseudomonas sp. QJX-1 under controlled illumination and carbon-limiting states. Chronological time-course sampling was executed to capture prokaryotic transcriptomic shifts (RNA-seq at 48h and 108h) and untargeted exometabolomic footprints (LC-MS at 48h, 72h, and 108h) to establish the molecular and chemical profiles driving phycosphere microscale redox coupling.
Morales Trujillo, Leticia · García García, Julián Alberto · Domínguez Mayo, Francisco José · et al.
11 rows × 3 cols · 1.1 KB · csv, png
3 categorical
This package provides the TRASYS validation and verification metamodel diagrams together with concise specifications of the model-to-model and model-to-text transformations documented in the doctoral thesis Continuous Traceability Management in Assisted Reproduction Processes. The materials describe the derivation of a preliminary verification model from a validation model and the generation of traceability-rule and data-structure code from the verification model. No clinical data, personal data, production code, Enterprise Architect project files, credentials, or proprietary artifacts are included.
Morales Trujillo, Letícia · Navarro Pando, José Manuel · García García, Julián Alberto · et al.
7 rows × 6 cols · 76 KB · xlsx
5 numeric · 1 categorical
This record contains the dataset associated with the systematic literature review titled "Image-Based Artificial Intelligence for Embryo Quality and Viability Assessment in Assisted Reproduction". The dataset includes the processed study records and the classification data used to answer the research questions. The files provided in this record are: (1) SLR_205_Processed_Articles.xlsx, containing the processed articles included in the review workflow; (2) SLR_RQ_Counts.xlsx, containing the counts and classifications associated with the research questions; and (3) README.txt, describing the repository contents and the search strategy applied in the consulted digital libraries. Searches were conducted in Scopus, IEEE Xplore, ScienceDirect, and ACM Digital Library using terms related to image analysis, artificial intelligence, and assisted reproductive technology. This dataset is shared to promote transparency, traceability, and reproducibility of the review process. All attached files can be viewed and downloaded directly from this Zenodo record: https://doi.org/10.5281/zenodo.19235464.
Der Datensatz "Daten der Notaufnahmesurveillance" wird durch das Robert Koch-Institut und das AKTIN-Notaufnahmeregister bei Krankenhausaufnahmen bereitgestellt. Der Datensatz beinhaltet aggregierte Routinedaten aus deutschen Notaufnahmen zur syndromischen Überwachung von akuten Erkrankungen. Dazu zählen grippeähnliche Erkrankungen (ILI), Coronavirus-Erkrankungen (COVID-19), akute respiratorische Erkrankungen (ARE), gastrointestinale Infektionen (GI) und schwere akute respiratorische Infektionen (SARI). Dabei wird der relative Anteil dieser Erkrankungen an der Gesamtzahl der Notaufnahmevorstellungen sowie die berechneten Erwartungswerte und Prädiktionsintervalle ausgewiesen. Die Daten sind nach Notaufnahmetypen und Altersgruppen aggregiert. Damit bietet der Datensatz eine wertvolle Ressource für die Forschung im Bereich der Notfallmedizin und der Überwachung akuter Gesundheitsereignisse in Deutschland.
This dataset originates from a study aiming to valorise Ciuta sheep, a local breed native from the Italian Central Alps, through the characterization of nutritional quality and chemical composition of fresh meat (loins) and one traditional dry-cured product. Specifically, the research focused on determining the chemical composition of Ciuta sheep meat and on identifying key changes in its chemical profile during dry curing process, hypothesizing that such chemical fingerprint may suggest some markers linked to the production system, geographical origin, and traditional processing techniques. For this reason, for bthe dry-cured product, both an aliquot of fresh meat before and after transformation and dry-curing was sampled and analysed. Regarding loins, three commercial categories (lambs, hoggets and mutton) were considered, in order to define any possible difference induced by age of the sheep (and physiological factors, such as rumen development). The dataset includes chemical data regarding the proximate composition (moisture, protein, fat, ash, salt content for the dry-cured product) and energy content of fresh and dry-cured meat; the fatty acids content of fresh and dry-cured meat product; the volatile profile of fresh and dry-cured meat product. Results from analysis performed in our study suggested that the development of high-quality dry-cured products could provide a strategy to valorise Ciuta sheep meat, especially from adult animals (culled ewes and rams), while fresh meat production could focus on lambs. The complex volatile profile detected was influenced by both the farming system and traditional processing methods.
File ini merupakan data mentah ( raw data ) ekspor dari database Scopus yang digunakan untuk melakukan pemetaan, analisis bibliometrik, atau Tinjauan Literatur Sistematis (SLR) mengenai tren riset di bidang Digital Humanities.